Anyone traveling with a disability in Honduras [1] will quickly realize that there are very few allowances made for anyone less mobile. The international chain hotels in the major cities are the best bets for wheelchair-friendly rooms (one lovely exception is La Casa Rosada in Copán Ruinas [2], which does have one wheelchair-accessible room).
Internal travel by plane or bus can be a challenge, although flight attendants on local puddle-jumpers are certainly accustomed to helping those with physical disabilities on and off the planes. Hiring a van with a driver is an easy option in Tegucigalpa [3], San Pedro Sula [4], La Ceiba [5], and Roatán [6].
Given that medical care is not on a par with that in the United States, any kind of emergency could be much more difficult to address.
Flying Wheels Travel (U.S. tel. 877/451-5006, www.flyingwheelstravel.com [7]) is a full-service travel agency that can make customized travel plans for travelers with disabilities who are traveling with able-bodied companions.
Links:
[1] http://www.moon.com/destinations/honduras
[2] http://www.moon.com/destinations/honduras/western-honduras/copan-ruinas/accommodations/us100-and
[3] http://www.moon.com/destinations/honduras/southern-honduras/tegucigalpa
[4] http://www.moon.com/destinations/honduras/central-honduras/san-pedro-sula
[5] http://www.moon.com/destinations/honduras/the-north-coast/la-ceiba
[6] http://www.moon.com/destinations/honduras/the-bay-islands/roatan
[7] http://www.flyingwheelstravel.com