The Museo de Los Altos de Chiapas (Ex-Convento del Templo de Santo Domingo de Guzmán, Av. 20 de Noviembre near Nicaragua, tel. 967/678-1609, 9 a.m.–6 p.m. daily, US$4) has interesting, if somewhat dated, exhibits on pre-Hispanic cultures, the arrival of the Spanish to San Cristóbal , and historic buildings in San Cristóbal. Signage is in Spanish, though there are English-language guidebooks at the entrance.
Upstairs is a temporary exhibit area that often shows impressive art collections. The building itself, the former convent of the Templo de Santo Domingo , has been beautifully restored with its high archways, polished wood floors, and thick stone and adobe walls.