St. Ignace  might not be the hottest nightlife spot in Michigan, but you will find at least one round-the-clock entertainment venue. The Kewadin Casino (3015 Mackinac Trail, 800/539-2346, www.kewadin.com ) promises Las Vegas–style gaming 24 hours daily and top-notch live entertainment on Friday and Saturday nights.
Situated on the shores of Lake Huron, the casino resort also offers an 81-room hotel, with plenty of amenities. Kewadin has four other casinos in the eastern Upper Peninsula, in the towns of Hessel, Manistique , Christmas, and Sault Ste. Marie .