Be sure to pull off Highway 12 at the Boynton Overlook (at the Escalante River bridge, 14 miles east of Escalante [1]) and scan the walls on the far side of the Escalante River for the Hundred Hands pictograph. (Binoculars help immensely.) For a closer look, hike 0.5 mile up from the parking lot just at the bottom of the hill, at the Escalante River crossing.
Rather than hike along the river, go up above the house (don’t stray onto fenced-in private property), scramble up the face of the first cliff, and follow faint trails and rock cairns across the bench. (It’s easiest if you’ve located the pictographs first from the overlook; this entire hike is just 0.5 mile round-trip.)
The Hundred Hands are high up on a cliff face that’s larger than the one you scrambled up. Follow the cliff to the right, where pictographs of goats are lower on the wall.
Back down at river level, head downstream a few hundred yards and look up to the left to see the Anasazi ruins known as the “Moki house.”
Links:
[1] http://www.moon.com/destinations/utah/the-escalante-region/escalante