Dominican padres established the last and shortest-lived of the Baja California missionary efforts, Misión Guadalupe, west of the current village in 1834.

In 1836, the mission was successfully defended against an attack by 400 Yumanos; four years later a much smaller force, led by a Neji Amerindian baptized at the mission, chased away the last Dominican padre.

The remains of the mission were incorporated into other buildings and are now difficult to identify.

Getting There

The Valle de Guadalupe is less than a two hour drive (70 mi) south of San Diego on the toll road from Tijuana to Ensenada.

After paying the last toll, watch for a sign to Tecate via Mexico 3 and the Ruta del Vino. Travel east on Mexico 3 for seven miles until you drop down into the Baja wine country at San Antonio de las Minas. This is the western end of the Guadalupe Valley wine region, which extends 14 miles east toward Tecate, ending near Km 73.5 at L. A. Cetto and Domecq wineries.